Daniel L. Hertz

I am a Cancer Clinical Pharmacology and Biomarker Scientist/Researcher.

Daniel L. Hertz, Pharm.D., Ph.D.

University of Michigan - Ann Arbor

My passion for cancer research and advocacy began when I lost my mom to breast cancer when I was 12. Later, as a PhD student in 2010, I began working on discovering predictive biomarkers of paclitaxel-induced peripheral neuropathy. When I found out in 2011 that my mom had received paclitaxel and experienced peripheral neuropathy, it made me feel closer to her than I had in years.

Daniel L. Hertz received a PharmD from the Ernest Mario School of Pharmacy at Rutgers University in 2008 and a PhD in Pharmaceutical Sciences from the UNC Eshelman School of Pharmacy in 2013. He has always had a passion for cancer research. During his graduate program, Dr. Hertz worked with Howard McLeod, who introduced him to the field of cancer pharmacogenetics. Dr. Hertz's dissertation research focused on discovery and validation of pharmacogenetic predictors of taxane-induced neuropathy. After receiving his PhD, Dr. Hertz joined the Department of Clinical Pharmacy at the University of Michigan College of Pharmacy, where he is currently an Associate Professor.

Dr. Hertz's current research focuses on developing tools for individualizing treatment in patients with cancer and translating them into clinical practice. His R37 uses data and biosamples collected on the prospective SWOG S1714 clinical trial to discover biomarkers (e.g., kinetics, genetics, metabolomics, nutrients) of taxane-induced peripheral neuropathy. These biomarkers could be used to identify patients at higher risk of neuropathy, in whom personalized treatment approaches or experimental preventive strategies can be investigated. This may lead to an improved standard of care that avoids long-term debilitating toxicity and improves treatment effectiveness.


Grant Listing
Project Title Grant Number Program Director Publication(s)
Development of an Integrated Risk Prediction Model of Taxane-induced Peripheral Neuropathy
1R37CA277043-01
Kelly Filipski


To request edits to this profile, please contact Mark Alexander at alexandm@mail.nih.gov.

Last Updated: 10/18/2023 09:26:57